Professor Vandry’s View Again the Racehorse theory for Joints! Collagen 1, 2, and 3, Vitamins and Minerals for the joints, Serrazyme Nattokinese (fibrinogen breakup), Lumen 90, and of course St. Jude’s Miracle Oil®!

Pain, nutrition, St. Judes Miracle Oil

by Professor William Vandry

Injuries are very common in any sport or Martial art.  I have certainly seen them, had them, and developed recovery angles.  Injuries such as sprains, or fractures or tissue tears are a common result of training in BJJ.  I have observed them yearly.  As many readers know, I write articles on the love and training of our Martial art of Jiu-jitsu.  There are many subjects to discuss, but a topic I delve into once in a while is a topic of injuries, and interesting supplements out there to look at.  I use a title called the Racehorse theory for a reason.  This theory is based on the concept of how racehorses are raised, trained and treated like top athletes.  Everything they do is a vital role in the racehorse.  Its diet, it’s training, cleaning, grooming, even time to play or develop out of training.  These are ways we as Martial artists should develop as well.  Research is available through Internet and through sources I study such as the NCBI medical journals and others.  For reference, my past articles on Racehorse theories are here:

1. BJJ In My Eyes April 2010: Treat Yourself like a racehorse!  (Vitamins and Minerals, Sleep and Pillow alignment, Inflammation and Magnesium, Serrapeptaste and Curcumin, Stress, Chiropractics and Massage)

2. William Vandry BJJ in My Eyes: Athletes, Anxiety, Depression, and the Vandry Racehorse Theory! 

3. Professor William Vandry’s View- May 2012 The Vandry Racehorse Theory!  The Vandry Racehorse theory: pain, arthritis, degenerative joint, tendon and ligaments, why athletes are so unhealthy, and medical doctors own health statistics and cholesterol life span

4. William Vandry- BJJ In My Eyes- April 2012- St. Jude’s Miracle Oil® created for pain, tension, inflammation and injuries  

 We are all athletes that practice Jiu-jitsu.  We all need rest, sleep, nutrition and supplementation.  We use our joints more frequently, and on a more frequent basis than the average person.  Due to this, joints began to wear down, and we develop conditions with ligaments, tendons, joints that develop chronic pain, or contribute to secondary effects.  Researching is a habit and passion of mine.  Like my BJJ style, I enjoy learning more about science and technology.  I certainly would be the first in line to look at peer science on supplementation.  Here is some research I found beginning with the importance of Collagen:

 Collagen 1, 2, and 3

Research shows that supplements of hydrolyzed types I and III collagen increase collagen levels in the skin. Types I and III collagen also support tendons and ligaments, and help with exercise recovery.  Type II collagen makes up a major portion of the cartilage that cushions joints. 

In osteoarthritis, injury or wear and tear break down cartilage, eventually causing bones to rub together.  Inflammation intensifies the symptoms but doesn’t trigger the disease.  In contrast, rheumatoid arthritis is an autoimmune disease, where inflammation causes pain, stiffness, and swelling.  It stems from an immune-system malfunction rather than ordinary wear and tear.

Collagen can actually help with both types of arthritis.

 Type II collagen naturally contains chondroitin and hyaluronic acid—substances known to support joint health. This is how they work together:

Type II collagen and chondroitin renew cartilage by providing building blocks and stimulating the body’s production of collagen. Chondroitin may also help fight inflammation and block an enzyme that breaks down cartilage. Hyaluronic acid, naturally found in synovial fluid, lubricates joints. (1)

 Exercise directly correlates with your tendons and joints via collagen 1 and 3 breakdown. (2)

 Dr. Marc Marrow, M.D. discusses valuable data on collagen:

 “The poor supply of blood to the ligaments and tendons is very apparent from their white color. Muscles on the other hand are red because they have a very good blood supply.  Ligaments and tendons therefore are prone to not heal completely from injury, because their limited blood supply does not offer, among other things, the supplies necessary to rebuild collagen.  Collagen and Degenerative Disc Disease, Collagen and Degenerative Joint Disease Most are familiar with collagen because of its cosmetic benefits. S kin is held together by collagen and young skin has plenty of it, making it smooth and wrinkle-free.  As we age, the quality and quantity of collagen diminishes and breaks down. Years of sun exposure, facial movement, and gravity aggravate the signs of age.  Wrinkles and creases appear; the cheeks are not as full; and the upper lip usually thins out.  Just as the collagen in our face deteriorates, so does the collagen in other parts of our body. This includes the ligaments and tendons in, and around, our joints. Where loss of collagen in our face is signified by wrinkles, in our joints it is signified by pain and a diagnosis of degenerative joint disease or Degenerative Disc Disease.”(3)

 Collagen II

 Collagen II is normally chicken cartilage.  There has been some positive research for cartilage repair.  Researching the NCBI medical journals, I found a very positive link with Collagen II and Rheumatoid Arthritis:

 “Positive effects were observed with CII at the lowest dosage tested, and the presence of serum antibodies to CII at baseline may predict response to therapy. No side effects were associated with this novel therapeutic agent. Further controlled studies are required to assess the efficacy of this treatment approach.”(4)

 I did find an Italy study attempting to use oral chicken cartilage with minimum effects, but their case should be studied from the Beth Israel Deaconess Medical Center, Boston, Massachusetts research noted above.  Furthermore, they should use the Harvard study on Collagen II on Rheumatoid Arthritis.  The study at Harvard was performed by David E. Trentham, Roselynn A. Dynesius-Trentham, E. John Orav, Daniel Combitchi, Carlos Lorenzo, Kathryn Lea Sewell, David A. Hafler, Howard L. Weiner and was published in the prestigious journal Science on September 24, 1993.  In the Harvard study, the chart clearly indicated results with RA patients taking Collagen II vs. Placebo:

1. Represents an increase of 30% or more from the entry value for the joint- significant (P = 0.10 by the x2 trend test. (5)

2. SIXTY PERCENT of the patients showed substantial clinical response and one patient showed a complete response in which the disease was totally eliminated for 26 months. More importantly, there were absolutely no side effects.

 These results were so profound that a 90 day, double blind, phase two study was conducted on 60 patients with very severe, active rheumatoid arthritis. It’s important to note that these patients were not beginning or moderate cases, but the most severe cases that can be usually encountered.   Patients either received the solubilized type II collagen or a placebo. (A placebo is a non-active type II collagen look-alike). The concentration was equivalent to that in the first study.

 At the end of the study, 59 of the 60 patients were evaluated.  Twenty-eight had received the collagen type II and 31 had received the placebo.

 Compared to the placebo group, the collagen type II group showed significant improvements in joint swelling, tenderness or pain.

This also included the degree of swelling and tenderness together. The doctors evaluated the response in a 15 meter walking time at months one, two and three. During the period at which the patients were taken off immunosuppressant drugs, those that received the collagen type II show stability and/or even improvement while those in the placebo group tended to deteriorate. However, four of the patients in the placebo group did show a significant placebo effect.

Four patients in the collagen type II group went into the next realm of the almost unbelievable, and showed a complete resolution of the disease.

 The Harvard Study was sponsored by Autoimmune, a Lexington, and Massachusetts biotechnology company. Only highly purified chicken sternal collagen type II was used. (6)

Vitamins and Minerals for the joints

 Vitamin C

Not only may vitamin C help reduce or prevent delayed onset muscle soreness due to exercise, it may also speed along recovery. Vitamin C helps our bodies produce collagen, which strengthens the connective tissue that forms our ligaments and tendons. When we’re injured, our requirements for vitamin C seem to increase. If too little is consumed, this will negatively impact the healing process. Getting enough vitamin C also helps limit further injury to damaged tissue and muscles. (7)

 I personally look at Vitamin C, and I have done research on Ascorbic acid vs. L-Ascorbate.  I prefer the non-synthetic L-Ascorbate.  I use a product from Beyond Health, a business that does research into health, supplements, disease prevention and nutrition.  Dr. Raymond Francis is the head, and his research is valid.  I prefer the buffered tablets of Vitamin C on his website. (8)

 Minerals for joints

 Manganese is a trace mineral that’s important for tissue repair and overall tendon and ligament health.  Manganese deficiency results in abnormal skeletal development in a number of animal species. Manganese is the preferred cofactor of enzymes called glycosyltransferases; these enzymes are required for the synthesis of proteoglycans that are needed for the formation of healthy cartilage and bone (9).

 Wound healing with Manganese

Wound healing is a complex process that requires increased production of collagen. Manganese is required for the activation of prolidase, an enzyme that functions to provide the amino acid, proline, for collagen formation in human skin cells. (10)

A genetic disorder known as prolidase deficiency results in abnormal wound healing among other problems, and is characterized by abnormal manganese metabolism. (11)

 Serrazyme Nattokinese (fibrinogen breakup)

Serrazyme or Serrapeptaste is can be read in a past article above (See Treat yourself like a Racehorse), so let me cut to the Nattokinese.

 Nattokinese (From WebMD):

 Nattokinase is an enzyme (a protein that speeds up biochemical reactions) that is extracted from a popular Japanese food called natto. Natto is boiled soybeans that have been fermented with a bacterium called Bacillus natto.  Nattokinase, the chemical in natto that is probably responsible for its effects, was discovered by a University of Chicago researcher, Dr. Hiroyuki Sumi.  You won’t find nattokinase in soy foods other than natto, since nattokinase is produced through the specific fermentation process used to make natto.  It is also used for pain, fibromyalgia, chronic fatigue syndrome, endometriosis, uterine fibroids, muscle spasms, infertility, cancer, and a vitamin-deficiency disease called beriberi.

 How does it work?

Nattokinase decreases the ability of blood to clot. This “thins the blood” and might protect against conditions caused by blood clots such as stroke, heart attack, and others. (12)

 What does Fibrin do?  It has some good points such as preventing clotting when bleeding.  The protein also has an opposite affect in the other direction.  On the Journal of Clinical Investigation relating Fibrin or fibrinogens to Joint Diseases: (13):

 “fibrin(ogen) is an important, but context-dependent, determinant of arthritis, and one mechanism linking fibrin(ogen) to joint disease is coupled to αMβ2-mediated inflammatory processes.  Fibrin deposition within joints is a prominent feature of arthritis”

 Nattokinese can be purchased at your local health store, or if you go to Amazon, there are many brands at comparable prices.

 Lumen 90

 I am amazed at this product.  I have read the medical journals, and my favorite Medical Doctor, Dr. Sherry Rogers has a monthly newsletter I read and has a plethora of medical information she researches for her customers.  I read about the Lumen 90 in one of her 2011 articles.  I am going to just insert a quote from Dr. Rogers on the Lumen, and I would suggest go to the website her article is posted on for more information:

 “As we age, our chances of developing hidden infection in tiny teeth roots increases exponentially. Having root canals, implants, extracted teeth (which leave cavitations), or cracks in teeth (especially around old fillings) all increase the chance of hidden infections. Therefore it makes a great deal of sense to wrap the Lumen pad around your mouth twice a day while you’re reading or watching TV. This can strengthen the immune function of the area, tighten the tiny ligaments that hold the teeth in, and ward off infection. Many of us have used it to avoid extraction. If this machine did nothing else, it would be important for everyone to have one just for this indication alone, since none of us wants to lose our teeth as we age. Yet everyone has pain at one time or another. Hips, knees, shoulders, and backs get tendonitis, fasciitis, bursitis, arthritis, burns, sprains, strains, ruptures, breaks, non-union or failure to heal fractures, localized chronic infections, falls, surgeries, auto accidents, and more.  The Lumen has a fascinating track record with pain relief after surgery or accidents, arthritis, accelerating the healing of sports injuries, healing of recalcitrant chronic problems like low back pain, shoulder and neck arthritis, herpes and regenerating nerves damaged by accidents or surgery. If you have diabetic ulcers or are contemplating amputation I would certainly check this out. For remember the New England Journal of Medicine article that showed a sham knee arthroscopy provided as much improvement as the real deal.” (14)   

 And last, my product, St. Jude’s Miracle Oil®

 My wife and I invented a product that came out last year called St. Jude’s Miracle Oil®.  The product is designed for its cooling, soothing, uplifting and relaxing effects.  Our product also won an INPEX international award for new inventions.  (See website for more info).  We are also happy to see my wife’s submitted article that will be published in the April 2013 Aromatherapy Today, International Aromatherapy Journal!

 The name St. Jude’s Miracle Oil® is a proprietary blend of 9 essential oils registered under the US Trademark and Patent office, and is protected by trademark and patent laws.  The special blend is a trade secret not public, and is also protected by law.

 The product has anti-inflammatory effects, and anti-viral, anti-bacterial and anti-histaminic actions.  Validating a product is important. Each particular oil can be referenced from medical journals and the Essential oils Desk reference book 5th edition.  For consumer information, the 9 essential oils in our product are:

 Wintergreen (Gaultheria procumbens), Peppermint (Mentha piperita), Lavender (Lavandula angustifolia), Eycalyptus Blue (Eucalyptus bicostata)Clove bud (Syzygium aromaticum, Geranium (Pelargonium graveolens), Clary Sage (Salvia sclarea), Frankincense (Boswellia carteri) and Myrrh (Commiphora myrrha).

 Essential oils have very little actual funding for research, although results have been shown in limited medical trials.  They do not require FDA approval, however manufacturers are not allowed to claim that they prevent or treat illness. We do not make claims such as those, but oils in our product have been used separately in clinical trials in medical journals I have researched.  I certainly look forward to actually funding clinical trials in the future with our oil, although they are very expensive which limits essential oil trials.  Regarding our joint issues, and athletic injuries, inflammation is where our problems start.  On separate trials, each oil has impressive results regarding inflammation in medical journals:

 Wintergreen acts as an anti-inflammatory agent (15-18).  The medicinal properties of peppermint oil are analgesic, anti-septic, anti-inflammatory, and antimicrobial, among others (19).  Lavender has anti-inflammatory and analgesic properties (20), and pain relief assessment (21).  Eucalyptus Blue has anti-inflammatory and analgesic properties (22), Clove bud has anti-infectious properties include: anti-viral, anti-bacterial, anti-fungal effects (23-24).  Geranium has shown temporary relief of neuralgia pain (25).  Clary Sage in pain relief on outpatients with primary dysmenorrhea (26).  Frankincense was used for symptomatic knee osteoarthritis (27) Myrrh oil has anti-inflammatory and analgesic activity (28)

So when you have joint issues, or soreness, consult your primary healthcare provider.  Reaearching some of these products can give us more information on what seems to be very common with athletes and people in general.

Absorb and think,

Professor William Vandry


 The information presented on this site is not intended for diagnostic or treatment purposes. Please consult your own physician for medical advice or services. The information provided on this website is intended for informational purposes only, and should not be considered a replacement for the expert advice of a qualified health practitioner. and makes no representations as to accuracy, completeness, current ness, suitability, or validity of any information on this site and will not be liable for any errors, omissions, or delays in this information or any losses, injuries, or damages arising from its display or use. All information is provided on an as-is basis










9. Keen CL, Zidenberg-Cherr S. Manganese. In: Ziegler EE, Filer LJ, eds. Present Knowledge in Nutrition. 7th ed. Washington D.C.: ILSI Press; 1996:334-343.

10. Muszynska A, Palka J, Gorodkiewicz E. The mechanism of daunorubicin-induced inhibition of prolidase activity in human skin fibroblasts and its implication to impaired collagen biosynthesis. Exp Toxicol Pathol. 2000;52(2):149-155.  (PubMed)

11. Shetlar MR, Shetlar CL. The role of manganese in wound healing. In: Klimis-Tavantzis DL, ed. Manganese in health and disease. Boca Raton: CRC Press, Inc.; 1994:145-157.




15. Methyl salicylate 2-O-β-D-lactoside, a novel salicylic acid analogue, acts as an anti-inflammatory agent on microglia and astrocytes.Lan X, Liu R, Sun L, Zhang T, Du G.J Neuroinflammation. 2011 Aug 11;8:98. doi: 10.1186/1742-2094-8-98.

16. A novel naturally occurring salicylic acid analogue acts as an anti-inflammatory agent by inhibiting nuclear factor-kappaB activity in RAW264.7 macrophages. Zhang T, Sun L, Liu R, Zhang D, Lan X, Huang C, Xin W, Wang C, Zhang D, Du G.Mol Pharm. 2012 Mar 5;9(3):671-7. doi: 10.1021/mp2003779. Epub 2012 Feb 15.

17. Anti-inflammatory activity of methyl salicylate glycosides isolated from Gaultheria yunnanensis (Franch.) Rehder.Zhang D, Liu R, Sun L, Huang C, Wang C, Zhang DM, Zhang TT, Du GH.  Molecules. 2011 May 9;16(5):3875-84. doi: 10.3390/molecules16053875

18. Evaluation of the new anti-inflammatory compound ethyl salicylate 2-O-β-d-glucoside and its possible mechanism of action.  Xin W, Huang C, Zhang X, Zhang G, Ma X, Sun L, Wang C, Zhang D, Zhang T, Du G.Int Immunopharmacol. 2012 Dec 4;15(2):303-308. doi:10.1016/j.intimp.2012.11.014.

19. Mullally BH, James JA, Coulter WA, Linden GJ. The efficacy of a herbal-based toothpaste on the control of plaque and gingivitis. J Clin Periodontol. 1995;22(9):686–9.

20. Hajhashemi, V., Ghannadi, A., & Sharif, B. (2003). Anti-inflammatory and analgesic properties of the leaf extracts and essential oil of lavandula angustifolia mill. Journal of Ethnopharmacology, 89(1), 67-71.(Lavender)

21. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.  Ou MC, Hsu TF, Lai AC, Lin YT, Lin CC.  SourceDepartment of Applied Cosmetology, Hungkuang University, Taichung, Taiwan

22. Phytochemical composition of Cymbopogon citratus and Eucalyptus citriodora essential oils and their anti-inflammatory and analgesic properties on Wistar rats.  Gbenou JD, Ahounou JF, Akakpo HB, Laleye A, Yayi E, Gbaguidi F, Baba-Moussa L, Darboux R, Dansou P, Moudachirou M, Kotchoni SO.  SourceLaboratoire de Pharmacognosie et des Huiles Essentielles, Faculté des Sciences de la Santé, Faculté des Sciences et Techniques, Université d’Abomey Calavi, 01 BP 918, Cotonou, Benin.

23. Antifungal activity of the clove essential oil from aromaticum on Candida, Aspergillus and dermatophyte species Euge´ nia Pinto,1 Luı´s Vale-Silva,1 Carlos Cavaleiro2 and Lı´gia Salgueiro2

24. Curr Med Chem. 2003 May;10(10):813-29.Antibacterial and antifungal properties of essential oils.  Kalemba D, Kunicka A.SourceInstitute of General Food Chemistry, Technical University of Lodz, Poland.

25. 20Greenway, f, Frome & Engels, T. (2003). Temporary relief of postherpetic neuralgia pain with topical geranium oil. American J of Medicine, 115, 586-587.

26. Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea: a randomized, double-blind clinical trial.  Ou MC, Hsu TF, Lai AC, Lin YT, Lin CC.  SourceDepartment of Applied Cosmetology, Hungkuang University, Taichung, Taiwan. [email protected]

27. Rheumatology (Oxford). 2013 Jan 30. Ayurvedic medicine offers a good alternative to glucosamine and celecoxib in the treatment of symptomatic knee osteoarthritis: a randomized, double-blind, controlled equivalence drug trial.  Source Center for Rheumatic Diseases, Pune, School of Biomedical Sciences, Symbiosis International University, Pune, BJ Medical College, Pune, Department of Rheumatology, Nizam Institute of Medical Sciences, Hyderabad, Department of Medicine, All India Institute of Medical Sciences, Delhi, Interactive Research School for Health Affairs, Bharati Vidyapeeth Deemed University, Pune, SPARC Institute, Mumbai, Department of Medicine, KEM Hospital, Mumbai and Symbiosis International University, Pune, India

28. Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha.  Source: Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Chinese Medicine, Nanjing 210046, PR China.



One Response to “Professor Vandry’s View Again the Racehorse theory for Joints! Collagen 1, 2, and 3, Vitamins and Minerals for the joints, Serrazyme Nattokinese (fibrinogen breakup), Lumen 90, and of course St. Jude’s Miracle Oil®!”

  1. Jen Says:

    This is such a helpful article Professor! We are in the process of getting our supplements in order and needed a guide to get us going. Thanks!

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